Deep Bone Infection: Modern Diagnostic Techniques, The Indication for Surgical Debridement, and the Prolonged Course of Therapy Required for Osteomyelitis
Osteomyelitis is a serious, often chronic, infection of the bone and bone marrow, usually caused by bacteria like Staphylococcus aureus, which can result from local trauma, open fractures, or hematogenous spread from a distant site of infection. Diagnosis requires a combination of clinical suspicion, advanced imaging (MRI is highly sensitive), blood tests, and, crucially, a bone biopsy to identify the causative organism and determine its antibiotic susceptibility profile.

